Chronic rhinosinusitis pathogenesis
نویسندگان
چکیده
منابع مشابه
Chronic rhinosinusitis in children.
Chronic rhinosinusitis (CRS) affects nearly 37 million people in the United States each year and accounts for approximately $6 billion in direct and indirect health care costs. Despite its prevalence and significant impact, little is known about its exact cause and pathophysiology, and significant controversy remains regarding appropriate treatment options. Basic science research, however, has ...
متن کاملChronic Rhinosinusitis in Children
Rhinosinusitis is a very common disease worldwide and specifically in the US population. It is a common disease in children but may be underdiagnosed. Several reasons may account to the disease being missed in children. The symptoms in children are limited and can be very similar to the common cold or allergic symptoms. Cough and nasal discharge may be the only symptoms present in children. A h...
متن کاملICON: chronic rhinosinusitis
Chronic rhinosinusitis (CRS) is a public health problem that has a significant socio-economic impact. Moreover, the complexity of this disease due to its heterogeneous nature based on the underlying pathophysiology - leading to different disease variants - further complicates our understanding and directions for the most appropriate targeted treatment strategies. Several International/national ...
متن کاملEpidemiology of chronic rhinosinusitis.
PROBLEM OF DEFINITION The discrepancy of definitions results mainly from the use of diVerent criteria such as symptom duration or intensity, the type of selected symptoms, and also from the need for and lack of other exploration methods such as imaging or bacteriological culture. In the definition proposed by the International Conference on Sinus Disease in 1993 the criteria for chronic sinusit...
متن کاملRole of epigenetics in the pathogenesis of chronic rhinosinusitis with nasal polyps
Chronic rhinosinusitis (CRS) is a highly prevalent disease characterized by mucosal inflammation of the nose and paranasal sinuses. CRS can be divided into two main categories, CRS with nasal polyps (NPs; CRSwNP) and CRS without NPs (CRSsNP). Although the pathophysiology of CRS remains unclear, DNA methylation has been implicated in the etiology of CRSwNP. The aim of the present study was to el...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2015
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2015.10.009